Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/74686
Type: Patent
Title: Comparative Genomic Hybridization
Author: Hussey, Nicole Dominique
Hu, Dong Gui
Issue Date: 2009
Assignee: Adelaide Research & Innovation Pty Ltd
School/Discipline: School of Paediatrics and Reproductive Health : Obstetrics and Gynaecology
Contributor: Dibbens Intellectual Property
Statement of
Responsibility: 
Invented by D. G. Hu, N. D. Hussey; Assigned to Adelaide Research & Innovation Pty Ltd; Dibbens Intellectual Property agents for inventors.
Abstract: The present invention relates to a method of comparing at least one chromosome or part thereof from a cell with a first karyotype with the corresponding chromosome or part thereof from a cell with a second karyotype. The method includes the steps of: (a) amplifying DNA from an isolated chromosome or part of an isolated chromosome; (b) attaching the amplified DNA to a solid substrate; (c) amplifying DNA from one or more cells with a first karyotype and amplifying DNA from one or more cells with a second karyotype; (d) labelling the amplified DNA from the one or more cells with a first karyotype with a first label, and labelling the amplified DNA from the one or more cells with a second karyotype with a second label, wherein the first and second labels are detectably different; (e) hybridizing the amplified and labelled DNA from the one or more cells with a first karyotype to the amplified DNA attached to the solid substrate, and hybridizing the amplified and labelled DNA from the one or more cells with a second karyotype to the amplified DNA attached to the solid substrate; and (f) comparing the relative amount of first and second labels hybridized to the amplified DNA attached to the solid substrate.
Description: PATENT: D. G. Hu, N. D. Hussey (Assignee: Adelaide Research & Innovation Pty Ltd). NZ 542860 (PCT/AU2004/000429) filed Apr. 02, 2004; Mar. 27, 2009; expires Apr. 02, 2024.
RMID: 0020114490
Published version: http://www.patentlens.net/patentlens/patent/WO_2004_088310_A1/en/
Appears in Collections:Obstetrics and Gynaecology publications

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