Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Immunoglobulin M capture immunoassay in investigation of coxsackie B5 and B6 outbreaks in South Australia|
|Citation:||Journal of Clinical Microbiology, 1995; 33(6):1628-1631|
|Publisher:||American Society for Microbiology|
|Abstract:||An immunoglobulin M (IgM) capture enzyme immunoassay was used to detect major overlapping outbreaks of disease in South Australia caused by coxsackieviruses B5 (CBV-5) and B6 (CBV-6). CBV-5-specific IgM was detected in patients presenting in spring 1992 with acute febrile illnesses, rash, severe acute respiratory disease, meningitis, myocarditis and/or pericarditis, while tests for other viruses were negative. CBV-5 was isolated from an early case. In December 1992 it was noted that CBV-6 had replaced CBV-5 as the major cause of disease. The CBV-6 epidemic continued until April 1993. Serum samples from 495 patients (276 inpatients) were submitted for testing. CBV-6 infection was associated with lower respiratory tract infection and persistent cough. This study demonstrated success of the IgM enzyme immunoassay and the need for diagnostic virology laboratories to look for CBV-6 infection in addition to the other five CBVs.|
|Keywords:||Humans; Enterovirus B, Human; Coxsackievirus Infections; Immunoglobulin M; Antibodies, Viral; Immunoenzyme Techniques; Sensitivity and Specificity; Disease Outbreaks; Adolescent; Adult; Child; Child, Preschool; Infant; Australia; Female; Male; Evaluation Studies as Topic|
|Description:||Copyright © 1995, American Society for Microbiology|
|Appears in Collections:||Paediatrics publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.