Adelaide Research & Scholarship
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https://hdl.handle.net/2440/75330
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| Type: | Journal article |
| Title: | Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid beta peptide |
| Author: | Kok, W. Scanlon, D. Karas, J. Miles, L. Tew, D. Parker, M. Barnham, K. Hutton, C. |
| Citation: | Chemical Communications, 2009; 7(41):6228-6230 |
| Publisher: | Royal Soc Chemistry |
| Issue Date: | 2009 |
| ISSN: | 1359-7345 1364-548X |
| Statement of Responsibility: | W. Mei Kok, Denis B. Scanlon, John A. Karas, Luke A. Miles, Deborah J. Tew, Michael W. Parker, Kevin J. Barnham and Craig A. Hutton |
| Abstract: | Covalently cross-linked homodimeric Aβ peptides have been prepared by solid-phase peptide synthesis by exploiting ‘site–site interactions’, and exhibit substantially increased oligomerisation and fibrillisation properties compared with the corresponding monomers. |
| Keywords: | Cross-Linking Reagents Amino Acid Sequence Molecular Sequence Data Protein Multimerization Amyloid beta-Peptides |
| Rights: | © The Royal Society of Chemistry 2009 |
| DOI: | 10.1039/b912784d |
| Grant ID: | NHMRC ARC |
| Published version: | http://dx.doi.org/10.1039/b912784d |
| Appears in Collections: | Aurora harvest 4 Medical Sciences publications |
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