Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/78905
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Type: Journal article
Title: Why is saline so acidic (and does it really matter?)
Author: Reddi, B.
Citation: International Journal of Medical Sciences, 2013; 10(6):747-750
Publisher: Ivyspring International Publisher
Issue Date: 2013
ISSN: 1449-1907
Statement of
Responsibility: 
Benjamin AJ Reddi
Abstract: Commercial 0.9% saline solution for infusion has a pH around 5.5. There are many reasons for this acidity, some of them still obscure. It is also true that infusion of normal saline can lead to met-abolic acidaemia, yet the link between the acidity of saline solution and the acidaemia it can en-gender is not straightforward. This commentary draws together the known and putative sources of acidity in saline solutions: it turns out that the acidity of saline solution is essentially unrelated to the acidaemia complicating saline infusion.
Keywords: saline; acidaemia; titratable acidity; crystalloid; balanced solution; Grotthuss.
Rights: © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/ licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
RMID: 0020128335
DOI: 10.7150/ijms.5868
Appears in Collections:Anaesthesia and Intensive Care publications

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