Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/79693
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Type: Journal article
Title: Mitral annulus calcification and sudden death
Author: Quick, E.
Byard, R.
Citation: Journal of Forensic and Legal Medicine, 2013; 20(4):204-206
Publisher: Churchill Livingstone
Issue Date: 2013
ISSN: 1752-928X
1878-7487
Statement of
Responsibility: 
Esther Quick, Roger W. Byard
Abstract: Mitral valve annulus calcification is a degenerative cardiac condition often found at autopsy in the elderly. While usually considered incidental to the cause of death, we report two cases where mitral valve annulus calcification with valve stenosis was associated with sudden death. Case 1: a 61-year-old female who had underlying atherosclerosis and hypertension collapsed at home. At autopsy there was marked mitral valve annulus calcification with valve stenosis and cardiomegaly. Case 2: a previously well 74-year-old female collapsed in a toilet. At autopsy there was marked calcification of the mitral valve annulus with valve stenosis. In both cases death was attributed to the effects of the calcified mitral valve annulus. Although such calcification may be unrelated to the terminal lethal mechanism, the association with left atrial enlargement, atrial fibrillation, mitral regurgitation, mitral stenosis, bacterial endocarditis, ischaemic and thromboembolic stroke, myocardial infarction, and arrhythmias, means that it should not be overlooked in the differential diagnosis in cases of sudden and unexpected death.
Keywords: Mitral annulus; mitral valve; calcification; sudden death; arrhythmia
Rights: © 2012 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.
RMID: 0020128135
DOI: 10.1016/j.jflm.2012.06.011
Appears in Collections:Pathology publications

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