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https://hdl.handle.net/2440/80195
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Type: | Journal article |
Title: | Prospective audit of vitamin D levels of women presenting for their first antenatal visit at a tertiary centre |
Author: | De Laine, K. Matthews, G. Grivell, R. |
Citation: | Australian and New Zealand Journal of Obstetrics and Gynaecology, 2013; 53(4):353-357 |
Publisher: | Blackwell Publishing Asia |
Issue Date: | 2013 |
ISSN: | 0004-8666 1479-828X |
Statement of Responsibility: | Kate M. De Laine, Geoff Matthews and Rosalie M. Grivell |
Abstract: | <h4>Background</h4>Vitamin D deficiency in pregnancy is associated with adverse events such as pre-eclampsia, primary caesarean section and vitamin D deficiency of the newborn. Vitamin D screening in pregnancy is not universal.<h4>Aims</h4>To evaluate the vitamin D status of pregnant women at our institution and assess the sensitivity of the current risk-based screening guideline.<h4>Methods</h4>A prospective audit of vitamin D levels of all women presenting for their first antenatal booking visit during 3 four-week periods (in 2009-2010) was conducted at the Women's and Children's Hospital, South Australia. The main outcome measure was 25-hydroxyvitamin D3 levels. Information was also collected on body mass index, self-reported ethnicity and whether or not vitamin D testing was indicated based on the hospital guidelines.<h4>Results</h4>Four hundred and seventy-two women consented to inclusion in the audit. 67.4% (318/472) were 'low-risk' according to the hospital guidelines for vitamin D screening. 46.2% of these women and 78.6% of 'high-risk' women were vitamin D deficient (<60 nmol/L). Mean vitamin D levels were 62.7 ± 22.0 and 43.4 ± 26.3 nmol/L for low- and high-risk women, respectively. 54.9% (147/268) of women who were found to be vitamin D deficient were classified as 'low-risk' giving a sensitivity of 45% for the current risk-based screening guideline.<h4>Conclusions</h4>Based on current normal ranges for vitamin D, risk-based screening criteria for vitamin D deficiency in pregnancy fails to detect over half of vitamin D deficient women at our institution. Current South Australian guidelines should be amended in favour of universal screening of vitamin D for all pregnant patients at their booking visit. |
Keywords: | pregnancy South Australia vitamin D |
Rights: | © 2013 The Authors |
DOI: | 10.1111/ajo.12052 |
Published version: | http://dx.doi.org/10.1111/ajo.12052 |
Appears in Collections: | Aurora harvest 4 Obstetrics and Gynaecology publications |
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