Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/81208
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorCaraguel, C.en
dc.contributor.authorVanderstichel, R.en
dc.date.issued2013en
dc.identifier.citationEvidence - Based Medicine, 2013; 18(4):125-128en
dc.identifier.issn1356-5524en
dc.identifier.issn1473-6810en
dc.identifier.urihttp://hdl.handle.net/2440/81208-
dc.description.abstractIn 1975, Fagan published a nomogram to help practitioners determine, without the use of a calculator or computer, the probability of a patient truly having a condition of interest given a particular test result. Nomograms are very useful for bedside interpretations of test results, as no test is perfect. However, the practicality of Fagan's nomogram is limited by its use of the likelihood ratio (LR), a parameter not commonly reported in the evaluation studies of diagnostic tests. The LR reflects the direction and strength of evidence provided by a test result and can be computed from the conventional diagnostic sensitivity (DSe) and specificity (DSp) of the test. This initial computation is absent in Fagan's nomogram, making it impractical for routine use. We have seamlessly integrated the initial step to compute the LR and the resulting two-step nomogram allows the user to quickly interpret the outcome of a test. With the addition of the DSe and DSp, the nomogram, for the purposes of interpreting a dichotomous test result, is now complete. This tool is more accessible and flexible than the original, which will facilitate its use in routine evidence-based practice. The nomogram can be downloaded at: www.adelaide.edu.au/vetsci/research/pub_pop/2step-nomogram/.en
dc.description.statementofresponsibilityCharles G B Caraguel, Raphaël Vanderstichelen
dc.language.isoenen
dc.publisherBMJ Groupen
dc.rights© 2013 the BMJ Publishing Group Ltd.en
dc.subjectHumans; Clinical Laboratory Techniques; Nomograms; Probability; Bayes Theorem; Sensitivity and Specificityen
dc.titleThe two-step Fagan's nomogram: ad hoc interpretation of a diagnostic test result without calculationen
dc.typeJournal articleen
dc.identifier.rmid0020131982en
dc.identifier.doi10.1136/eb-2013-101243en
dc.identifier.pubid17886-
pubs.library.collectionAnimal and Veterinary Sciences publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidCaraguel, C. [0000-0003-0019-4813]en
Appears in Collections:Animal and Veterinary Sciences publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.