Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/81906
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Type: Journal article
Title: Paediatric active enhanced disease surveillance: a new surveillance system for Australia
Author: Zurynski, Y.
McIntyre, P.
Booy, R.
Elliott, E.
PAEDS Investigators Group.,
Citation: Journal of Paediatrics and Child Health, 2013; 49(7):588-594
Publisher: Wiley-Blackwell
Issue Date: 2013
ISSN: 1034-4810
1440-1754
Department: Faculty of Health Sciences
Organisation: Robinson Institute
Contributor: Marshall, Helen Siobhan
Statement of
Responsibility: 
Yvonne Zurynski, Peter McIntyre, Robert Booy, and Elizabeth J Elliott, on behalf of the PAEDS Investigators Group (PAEDS Investigators Group contributor: Professor Helen Marshall for the University of Adelaide)
Abstract: AIM The Paediatric Active Enhanced Disease Surveillance (PAEDS) is described. PAEDS is active in four tertiary children's hospitals in four states of Australia and aims to address gaps in surveillance for severe vaccine-preventable diseases and adverse events following immunisation. METHODS From August 2007 to December 2010, surveillance nurses actively identified and recruited children admitted with: acute flaccid paralysis, varicella infection, intussusception, seizures in infants and pandemic influenza (June–October 2009). Details of presentation, medical and immunisation history, outcome and laboratory results were collected. Completeness of ascertainment was estimated through audits of International Classification of Diseases 10th edition-coded medical records where possible. RESULTS Seven hundred thirty-three cases matching case definition criteria for the four conditions were recruited. In addition, 601 cases of influenza were recruited during the 2009 pandemic. PAEDS enhanced acute flaccid paralysis surveillance by the Australian Paediatric Surveillance Unit; the World Health Organization surveillance target was met when Australian Paediatric Surveillance Unit and PAEDS cases were combined. Among 133 children hospitalised for varicella, only 16 were vaccinated; samples of vesicle scrapings were collected in 57% for genotyping. Of 122 infants presenting with seizures, only six (12%) had received a vaccine in the last 7 days. Intussusception was more frequent among infants receiving their first dose of either of the rotavirus vaccines. Results informed policy and education for parents and health professionals. Preliminary audits of medical records suggest excellent ascertainment through PAEDS. CONCLUSIONS PAEDS provides important, previously unavailable data to inform public health policy, clinical practice and community confidence. It has potential to respond quickly during outbreaks and epidemics.
Keywords: Child; immunisation; infectious disease; surveillance system
Description: Accepted for publication 23 December 2012.
Rights: © 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians)
DOI: 10.1111/jpc.12282
Grant ID: http://purl.org/au-research/grants/nhmrc/402784
http://purl.org/au-research/grants/nhmrc/457084
http://purl.org/au-research/grants/nhmrc/1021480
Published version: http://dx.doi.org/10.1111/jpc.12282
Appears in Collections:Aurora harvest 3
Paediatrics publications

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