Endocytoscopy for diagnosis of gastrointestinal neoplasia: the expert's approach

Abstract

Endocytoscopy is an ultra-high magnification technique that enables surface morphology to be assessed in real time, with magnifications in excess of 450×. This technology uses a high-power fixed-focus objective lens. The device can either be incorporated into the endoscope or comes in a probe-based system.This promising device could potentially be used throughout the gastrointestinal tract, enabling further characterization of pathology such as dysplasia or early cancer in Barrett's esophagus, villous and cellular morphology in patients with suspicion of celiac disease, or assessing and differentiating colonic polyps in real time. The accompanying video will demonstrate the technique of endocytoscopy and its potential applications. This article is part of an expert video encyclopedia. © 2013 Elsevier GmbH.