Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/8424
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Type: Journal article
Title: A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy
Author: Smith, C.
Crowther, C.
Willson, K.
Hotham, N.
McMillian, V.
Citation: Obstetrics and Gynecology, 2004; 103(4):639-645
Publisher: Lippincott Williams & Wilkins
Issue Date: 2004
ISSN: 0029-7844
1873-233X
Statement of
Responsibility: 
Smith, Caroline; Crowther, Caroline; Willson, Kristyn; Hotham, Neil; McMillian, Vicki
Abstract: Objectives: To estimate whether the use of ginger to treat nausea or vomiting in pregnancy is equivalent to pyridoxine hydrochloride (vitamin B6). Methods: A randomized, controlled equivalence trial involving 291 women less than 16 weeks pregnant was undertaken at a teaching hospital in Australia. Women took 1.05 g of ginger or 75 mg of vitamin B6 daily for 3 weeks. Differences from baseline in nausea and vomiting scores were estimated for both groups at days 7, 14, and 21. Results: Ginger was equivalent to vitamin B6 in reducing nausea (mean difference 0.2, 90% confidence interval [CI] -0.3, 0.8), retching (mean difference 0.3; 90% CI -0.0, 0.6) and vomiting (mean difference 0.5; 90% CI 0.0, 0.9), averaged over time, with no evidence of different effects at the 3 time points. Conclusion: For women looking for relief from their nausea, dry retching, and vomiting, the use of ginger in early pregnancy will reduce their symptoms to an equivalent extent as vitamin B6.
Keywords: Humans; Ginger; Pregnancy Complications; Nausea; Vomiting; Vitamin B 6; Plant Preparations; Pregnancy Outcome; Treatment Outcome; Phytotherapy; Severity of Illness Index; Single-Blind Method; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Adult; Female
Description: © 2004 The American College of Obstetricians and Gynecologists
RMID: 0020041155
DOI: 10.1097/01.AOG.0000118307.19798.EC
Description (link): http://www.greenjournal.org/cgi/content/abstract/103/4/639
Appears in Collections:Obstetrics and Gynaecology publications

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