Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/8493
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Type: Journal article
Title: Obesity and reproductive disorders: a review
Author: Norman, R.
Clark, A.
Citation: Reproduction, Fertility and Development, 1998; 10(1):55-63
Publisher: CSIRO Publishing
Issue Date: 1998
ISSN: 1031-3613
1448-5990
Statement of
Responsibility: 
R. J. Norman and A. M. Clark
Abstract: Obesity has significant consequences for the reproductive system, depending upon the amount and distribution of body fat. Epidemiological evidence clearly shows that being overweight contributes to menstrual disorders, infertility, miscarriage, poor pregnancy outcome, impaired fetal well-being and diabetes mellitus. Central adiposity is particularly important in clinical sequelae associated with an increased body mass index. The advent of assisted reproduction highlights the problems of being overweight, and the use of gonadotrophins in ovulation induction and in vitro fertilization is more difficult when the subject is overweight. Weight loss has marked effects on improving the menstrual cycle and promoting spontaneous ovulation and fertility. Results indicate that fertility is improved through exercise and sensible eating patterns when conducted in a group environment. The mechanisms for this are unclear but may be associated with changes in sensitivity to insulin.
Keywords: Adipose Tissue; Humans; Infertility, Female; Pregnancy Complications; Abortion, Spontaneous; Glucose Intolerance; Obesity; Menstruation Disturbances; Weight Loss; Androgens; Estrogens; Pregnancy Outcome; Pregnancy; Adult; Aged; Middle Aged; Female; Male
Rights: © CSIRO Australia 1998
RMID: 0030005180
DOI: 10.1071/R98010
Appears in Collections:Obstetrics and Gynaecology publications

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