Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/85728
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Type: Journal article
Title: Increased and decreased sensitivity to carbon catabolite repression of enzymes of acetate metabolism in mutants of Aspergillus nidulans
Author: Kelly, J.
Hynes, M.
Citation: Molecular and General Genetics MGG, 1977; 156(1):87-92
Publisher: Springer-Verlag
Issue Date: 1977
ISSN: 0026-8925
1432-1874
Statement of
Responsibility: 
Joan M. Kelly and M.J. Hynes
Abstract: The creA204, creB15 and creC27 mutations have been shown to cause carbon catabolite derepression of acetyl CoA synthase and isocitrate lyase in Aspergillus nidulans. A recessive mutation, cre-34, which is linked to the creC gene, results in these enzymes being more sensitive than cre or wildtype strains to catabolite repression. The acetamidase levels of strains containing cre mutations have been investigated and provide support for the hypothesis that an acetate metabolite, rather than acetamide, induces this enzyme.
Keywords: Aspergillus nidulans; Acetates; Aminohydrolases; Coenzyme A Ligases; Acetate-CoA Ligase; Oxo-Acid-Lyases; Isocitrate Lyase; Enzyme Repression; Genes, Recessive; Mutation
Rights: © by Springer-Verlag 1977
RMID: 0030008827
DOI: 10.1007/BF00272256
Appears in Collections:Genetics publications

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