Adelaide Research & Scholarship
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https://hdl.handle.net/2440/85911
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| Type: | Journal article |
| Title: | Preparation of (–)-(7R)-7-acetyl-7-hydroxy-4,4-dimethoxy-5,6,7,8-tetrahydro-naphthalen-1(4H)-one, a chiral AB-synthon for anthracycline synthesis |
| Author: | Warrener, R. Gee, P. Russell, R. |
| Citation: | Journal of the Chemical Society, Chemical Communications, 1981; 1981(21):1100-1101 |
| Publisher: | Royal Society of Chemistry |
| Issue Date: | 1981 |
| ISSN: | 0022-4936 |
| Statement of Responsibility: | Ronald N. Warrener, Paul S. Gee and Richard A. Russell |
| Abstract: | The (–)-(R)-dienone (13) was prepared in 10 steps from the known 8-hydroxy-5-methoxy-2, 3-dihydronaphthalen-1(4H)-one (2), and the chirality at C(7) in (13) corresponds to that found at C(9) in the naturally occurring anthracyclines related to daunomycin. |
| Rights: | Copyright status unknown |
| DOI: | 10.1039/c39810001100 |
| Appears in Collections: | Aurora harvest 7 Chemistry publications |
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