Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/86969
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Type: Journal article
Title: A nanoporous interferometric micro-sensor for biomedical detection of volatile sulphur compounds
Author: Kumeria, T.
Parkinson, L.
Losic, D.
Citation: Nanoscale Research Letters, 2011; 6(1):634-1-634-7
Publisher: SpringerOpen
Issue Date: 2011
ISSN: 1931-7573
1556-276X
Statement of
Responsibility: 
Tushar Kumeria, Luke Parkinson and Dusan Losic
Abstract: This work presents the use of nanoporous anodic aluminium oxide [AAO] for reflective interferometric sensing of volatile sulphur compounds and hydrogen sulphide [H2S] gas. Detection is based on changes of the interference signal from AAO porous layer as a result of specific adsorption of gas molecules with sulphur functional groups on a gold-coated surface. A nanoporous AAO sensing platform with optimised pore diameters (30 nm) and length (4 µm) was fabricated using a two-step anodization process in 0.3 M oxalic, followed by coating with a thin gold film (8 nm). The AAO is assembled in a specially designed microfluidic chip supported with a miniature fibre optic system that is able to measure changes of reflective interference signal (Fabry-Perrot fringes). When the sensor is exposed to a small concentration of H2S gas, the interference signal showed a concentration-dependent wavelength shifting of the Fabry-Perot interference fringe spectrum, as a result of the adsorption of H2S molecules on the Au surface and changes in the refractive index of the AAO. A practical biomedical application of reflectometric interference spectroscopy [RIfS] Au-AAO sensor for malodour measurement was successfully shown. The RIfS method based on a nanoporous AAO platform is simple, easy to miniaturise, inexpensive and has great potential for development of gas sensing devices for a range of medical and environmental applications.
Keywords: nanoporous alumina; reflectometric interference spectroscopy; volatile sulphur compounds; hydrogen sulphide sensor; oral malodour
Rights: © 2011 Kumeria et al; licensee Springer. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
RMID: 0020116504
DOI: 10.1186/1556-276X-6-634
Grant ID: http://purl.org/au-research/grants/arc/DP0770930
Appears in Collections:Chemical Engineering publications

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