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|Title:||Associations between aggressive behaviour scores and cardiovascular risk factors in childhood|
|Citation:||Pediatric Obesity, 2012; 7(4):319-328|
|S. Louise, N.M. Warrington, P.A. McCaskie, W.H. Oddy, S.R. Zubrick, B. Hands, T.A. Mori, L. Briollais, S. Silburn, L.J. Palmer, E. Mattes and L.J. Beilin|
|Abstract:||OBJECTIVE: To examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood. METHODS: This study utilized cross-sectional and longitudinal data from the Western Australian Pregnancy Cohort (Raine) Study (n = 2900). Aggressive behaviour scores were derived from the Child Behavior Checklist/4–18(CBCL), Youth Self-Report/11–18 (YSR) and Teacher Report Form/6–18 (TRF). CVD risk factors included body mass index (BMI), blood pressure, fasting lipids and homeostasis model of insulin resistance (HOMA-IR). RESULTS: Girls with higher aggressive behaviour scores had higher BMI from 10 years of age (P ≤ 0.001), higher BMI trajectories throughout childhood (P = 0.0003) and at 14 years higher HOMA-IR (P = 0.008). At the 14-year survey, this equated to a difference of 1.7 kg/m2 in the predicted BMI between the extreme CBCL scores in girls (top 5% (CBCL ≥ 17) vs. CBCL score = 0). Boys with higher aggressive behaviour scores had higher BMI at 5 years (P = 0.002), lower diastolic pressure at 14 years (P = 0.002) and lower systolic blood pressure trajectories throughout childhood (P = 0.016). CONCLUSION: Aggressive behaviour influences BMI from early childhood in girls but not boys. If this association is causal, childhood offers the opportunity for early behavioural intervention for obesity prevention.|
|Keywords:||Aggression; cardiovascular disease; Raine Study; risk factors|
|Rights:||© 2012 The Authors Pediatric Obesity © 2012 International Association for the Study of Obesity|
|Appears in Collections:||Translational Health Science publications|
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