Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/90042
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Type: Journal article
Title: Microbiota and their role in the pathogenesis of oral mucositis
Author: Vanhoecke, B.
De Ryck, T.
Stringer, A.
Van de Wiele, T.
Keefe, D.
Citation: Oral Diseases, 2015; 21(1):17-30
Publisher: Wiley
Issue Date: 2015
ISSN: 1354-523X
1601-0825
Statement of
Responsibility: 
B Vanhoecke, T De Ryck, A Stringer, T Van de Wiele and D Keefe
Abstract: Oral mucositis in patients undergoing cancer therapy is a significant problem. Its prevalence ranges between 20 and 100%, depending on treatment type and protocols and patient-based variables. Mucositis is self-limiting when uncomplicated by infection. Unfortunately, the incidence of developing a local or systemic infection during the course of the treatment is very high. At this stage, it is unclear which role oral microbiota play in the onset, duration, and severity of oral mucositis. Nevertheless, there is growing interest in this underexplored topic, and new studies are being undertaken to unravel their impact on the pathogenesis of mucositis.
Keywords: oral; mucositis; microbiota; biofilm; radiotherapy; chemotherapy
Rights: © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.
RMID: 0030021283
DOI: 10.1111/odi.12224
Appears in Collections:Medicine publications

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