Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9092
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dc.contributor.authorMalbert, C.en
dc.contributor.authorMathis, C.en
dc.contributor.authorBobillier, E.en
dc.contributor.authorLaplace, J.en
dc.contributor.authorHorowitz, M.en
dc.date.issued1997en
dc.identifier.citationNeurogastroenterology and Motility, 1997; 9(3):157-165en
dc.identifier.issn1350-1925en
dc.identifier.issn1365-2982en
dc.identifier.urihttp://hdl.handle.net/2440/9092-
dc.description.abstractGastric emptying is usually measured in animals and humans by dilution/sampling or external scintigraphy. These methods are either time consuming or require expensive equipment. The capacity of a miniature gamma counter positioned in the stomach to measure emptying of liquid and solid meals was evaluated. In eight conscious pigs fitted with gastric and duodenal cannulae, gastric emptying of saline (500 mL), dextrose (20%, 500 mL), porridge (300 g) and scrambled eggs (300 g), all labelled with 3.5 MBq 99mTC, was evaluated. When positioned in the antrum the probe was unable to quantify gastric emptying. In contrast, measurements of the fractional emptying of saline over 4-min periods by the probe positioned in the corpus and quantification of radioactivity in the duodenal effluent correlated closely (r = 0.88, P < 0.05). Gastric emptying (50% emptying time) of saline and both solid meals measured by the probe was not significantly different from quantification of the duodenal effluent volume. No difference was observed also for the dextrose meal but only while gastric acid secretion was suppressed by omeprazole. We conclude that an intragastric gamma counter permits measurement of gastric emptying of homogeneous meals provided meal stimulation of gastric secretion was not extensive. This was possible probably by monitoring emptying from the proximal stomach.en
dc.description.statementofresponsibilityC. H. Malbert, C. Mathis, E. Bobillier, J. P. Laplace, M. Horowitzen
dc.language.isoenen
dc.publisherBLACKWELL SCIENCE LTDen
dc.subjectDuodenum; Stomach; Animals; Swine; Cadmium; Scintillation Counting; Gastric Emptying; Pressureen
dc.titleMeasurement of gastric emptying by intragastric gamma scintigraphyen
dc.typeJournal articleen
dc.identifier.rmid0030004793en
dc.identifier.doi10.1046/j.1365-2982.1997.d01-38.xen
dc.identifier.pubid68799-
pubs.library.collectionMedicine publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
Appears in Collections:Medicine publications

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