Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/9787
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kucia, A. | - |
dc.contributor.author | Horowitz, J. | - |
dc.date.issued | 2000 | - |
dc.identifier.citation | American Heart Journal, 2000; 140(1):94-97 | - |
dc.identifier.issn | 0002-8703 | - |
dc.identifier.issn | 1097-5330 | - |
dc.identifier.uri | http://hdl.handle.net/2440/9787 | - |
dc.description.abstract | <h4>Methods</h4>Patient understanding of clinical trial details was assessed on 2 occasions (10 +/- 4 and 24 +/- 3 hours after randomization) in 20 patients enrolled for randomized investigation of pharmacotherapy for unstable angina pectoris or non-Q-wave myocardial infarction in the Platelet IIb/IIIa Antagonist for the Reduction of Acute Coronary Syndrome Events in a Global Organized Network (PARAGON B) and Organization to Assess Strategies in Ischemic Syndromes (OASIS-2) trials.<h4>Results</h4>Initial total score for understanding of 52.0% (+/-15.7%) of maximal values improved to 67.7% (+/-18.3%) at repeat interview (P <.001). The mean initial score for knowledge of potential benefit was 85.0% (+/-33.3%) with no significant improvement at repeat interview. Scores for knowledge of risk improved from 35.0% (+/-36.6%) to 68.2% (+/-41.2%) at repeat interview (P <.005). Significant determinants of poor initial score were female sex, limited education, and presence of pain during the consent process; young age was the only determinant of improvement on repeat assessment.<h4>Conclusion</h4>Thus initial understanding of the research protocols for patients with unstable angina pectoris or non-Q-wave acute myocardial infarction was imperfect, with far greater impairment of knowledge of risk than of benefit. | - |
dc.language.iso | en | - |
dc.publisher | Mosby Inc | - |
dc.source.uri | http://dx.doi.org/10.1067/mhj.2000.106625 | - |
dc.subject | Humans | - |
dc.subject | Coronary Disease | - |
dc.subject | Angina, Unstable | - |
dc.subject | Myocardial Infarction | - |
dc.subject | Syndrome | - |
dc.subject | Platelet Aggregation Inhibitors | - |
dc.subject | Multivariate Analysis | - |
dc.subject | Probability | - |
dc.subject | Risk Factors | - |
dc.subject | Double-Blind Method | - |
dc.subject | Health Knowledge, Attitudes, Practice | - |
dc.subject | Age Factors | - |
dc.subject | Informed Consent | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.subject | Clinical Trials as Topic | - |
dc.subject | Surveys and Questionnaires | - |
dc.title | Is informed consent to clinical trials an "upside selective" process in acute coronoary syndromes? | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1067/mhj.2000.106625 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Kucia, A. [0000-0002-7606-7717] | - |
dc.identifier.orcid | Horowitz, J. [0000-0001-6883-0703] | - |
Appears in Collections: | Aurora harvest 4 Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.