Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/99760
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Type: Journal article
Title: Physical inactivity is associated with moderate-severe obstructive sleep apnea
Author: Simpson, L.
McArdle, N.
Eastwood, P.
Ward, K.
Cooper, M.
Wilson, A.
Hillman, D.
Palmer, L.
Mukherjee, S.
Citation: Journal of Clinical Sleep Medicine, 2015; 11(10):1091-1099A
Publisher: American Academy of Sleep Medicine
Issue Date: 2015
ISSN: 1550-9389
1550-9397
Statement of
Responsibility: 
Laila Simpson, Nigel McArdle, Peter R. Eastwood, Kim L. Ward, Matthew N. Cooper, Annette C. Wilson, David R. Hillman, Lyle J. Palmer, Sutapa Mukherjee
Abstract: Study Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk. Methods: A case-control study design was used. OSA cases were patients referred to a sleep clinic for suspected OSA (n = 2,340). Controls comprised participants from the Busselton community (n = 1,931). Exercise and occupational activity were derived from questionnaire data. Associations were modelled using logistic and linear regression and adjusted for confounders. Results: In comparison with moderate exercise, the high, low, and nil exercise groups had an odds ratio (OR) for moderate-severe OSA of 0.6 (95% CI 0.5–0.8), 1.6 (95% CI 1.2–2.0), and 2.7 (95% CI 1.9–3.7), respectively. Relative to men in heavy activity occupations, men in medium, light and sedentary occupations had an OR for moderate-severe OSA of 1.7 (95% CI 1.1–2.5), 2.1 (95% CI 1.4–3.2), and 1.8 (95% CI 1.2–2.8), respectively. Relative to women in medium activity occupations, women in light and sedentary occupations had an OR for moderate-severe OSA of 4.2 (95% CI 2.6–7.2) and 3.5 (2.0–6.0). OSA patients who adequately exercised had lower: levels of doctor-diagnosed depression (p = 0.047); symptoms of fatigue (p < 0.0001); systolic (p = 0.015) and diastolic blood pressure (p = 0.015); and C-reactive protein (CRP) (p = 0.003). Conclusions: Low levels of physical activity were associated with moderate-severe OSA. Exercise in individuals with OSA is associated with lower levels of depression, fatigue, blood pressure and CRP.
Keywords: weight; sleep disordered breathing; cardio metabolic; occupation; exercise
Rights: Copyright status unknown
RMID: 0030039140
DOI: 10.5664/jcsm.5078
Grant ID: http://purl.org/au-research/grants/nhmrc/1042341
Appears in Collections:Translational Health Science publications

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