Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/118692
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Type: | Journal article |
Title: | Association between multimorbidity and undiagnosed obstructive sleep apnea severity and their impact on quality of life in men over 40 years old |
Author: | Ruel, G. Martin, S.A. Lévesque, J.-F. Wittert, G.A. Adams, R.J. Appleton, S.L. Shi, Z. Taylor, A.W. |
Citation: | Global Health, Epidemiology and Genomics, 2018; 3:e10-e10 |
Publisher: | Cambridge University Press (CUP) |
Issue Date: | 2018 |
ISSN: | 2054-4200 2054-4200 |
Statement of Responsibility: | G. Ruel, S. A. Martin, J.-F. Lévesque, G. A. Wittert, R. J. Adams, S. L. Appleton, Z. Shi and A. W. Taylor |
Abstract: | Background:Multimorbidity is common but little is known about its relationship with obstructive sleep apnea (OSA). Methods:Men Androgen Inflammation Lifestyle Environment and Stress Study participants underwent polysomnography. Chronic diseases (CDs) were determined by biomedical measurement (diabetes, dyslipidaemia, hypertension, obesity), or self-report (depression, asthma, cardiovascular disease, arthritis). Associations between CD count, multimorbidity, apnea-hyponea index (AHI) and OSA severity and quality-of-life (QoL; mental & physical component scores), were determined using multinomial regression analyses, after adjustment for age. Results:Of the 743 men participating in the study, overall 58% had multimorbidity (2+ CDs), and 52% had OSA (11% severe). About 70% of those with multimorbidity had undiagnosed OSA. Multimorbidity was associated with AHI and undiagnosed OSA. Elevated CD count was associated with higher AHI value and increased OSA severity. Conclusion:We demonstrate an independent association between the presence of OSA and multimorbidity in this representative sample of community-based men. This effect was strongest in men with moderate to severe OSA and three or more CDs, and appeared to produce a greater reduction in QoL when both conditions were present together. |
Keywords: | Apnea-hypopnea index chronic disease comorbidity obstructive sleep apnea quality of life |
Rights: | © The Author(s) 2018 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
DOI: | 10.1017/gheg.2018.9 |
Published version: | http://dx.doi.org/10.1017/gheg.2018.9 |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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hdl_118692.pdf | Published version | 819.51 kB | Adobe PDF | View/Open |
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