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PreviewIssue DateTitleAuthor(s)
2001In vivo perturbation of rat hepatocyte canalicular membrane function by diclofenacSallustio, B.; Holbrook, F.
2000Hepatic disposition of the acyl glucoronide 1-O-gemfibrozil--D-glucoronide: Effects of clofibric acid, acetaminophen, and acetaminophen glucuronideSabordo, L.; Sallustio, B.; Evans, A.; Nation, R.
2004Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7Toutsikos, P.; Miners, J.; Stapleton, A.; Thomas, A.; Sallustio, B.; Knights, K.
2008Steady-state pharmacokinetics of the enantiomers of perhexiline in CYP2D6 poor and extensive metabolizers administered Rac-perhexilineDavies, B.; Herbert, M.; Coller, J.; Somogyi, A.; Milne, R.; Sallustio, B.
2004Optimisation of the comet genotoxicity assay in freshly isolated murine hepatocytes: detection of strong in vitro DNA damaging properties for styreneFontaine, F.; DeGraaf, Y.; Ghaoui, R.; Sallustio, B.; Edwards, J.; Burcham, P.
2003UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytesGhaoui, R.; Sallustio, B.; Burcham, P.; Fontaine, F.
2004Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexilineDavies, B.; Coller, J.; James, H.; Gillis, D.; Somogyi, A.; Horowitz, J.; Morris, R.; Sallustio, B.
2006Role of MRP2 in the hepatic disposition of mycophenolic acid and its glucuronide metabolites: Effect of cyclosporineWestley, I.; Brogan, L.; Morris, R.; Evans, A.; Sallustio, B.
2000In vitro covalent binding of Nafenopin-CoA to human liver proteinsSallustio, B.; Nunthasomboon, S.; Drogemuller, C.; Knights, K.
2006Bioactivation of carboxylic acid compounds by UDP-glucuronosyltransferases to DNA-damaging intermediates: Role of glycoxidation and oxidative stress in genotoxicitySallustio, B.; DeGraaf, Y.; Weekley, J.; Burcham, P.