Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/17458
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DC Field | Value | Language |
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dc.contributor.author | Seshadri, T. | - |
dc.contributor.author | Prince, H. | - |
dc.contributor.author | Bell, D. | - |
dc.contributor.author | Coughlin, P. | - |
dc.contributor.author | James, P. | - |
dc.contributor.author | Richardson, G. | - |
dc.contributor.author | Chern, B. | - |
dc.contributor.author | Briggs, P. | - |
dc.contributor.author | Norman, J. | - |
dc.contributor.author | Olver, I. | - |
dc.contributor.author | Karapetis, C. | - |
dc.contributor.author | Stewart, J. | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | Medical Journal of Australia, 2005; 182(9):453-457 | - |
dc.identifier.issn | 0025-729X | - |
dc.identifier.issn | 1326-5377 | - |
dc.identifier.uri | http://hdl.handle.net/2440/17458 | - |
dc.description | The document attached has been archived with permission from the editor of the Medical Journal of Australia (09 January 2008). An external link to the publisher’s copy is included. | - |
dc.description.abstract | Objective: To evaluate the frequency and management of anaemia in Australian adults with solid and haematological malignancies. Design: 6-month observational, prospective, multicentre study. Participants: 694 patients recruited from outpatient oncology clinics in 24 hospitals in five Australian states between 9 April 2001 and 31 July 2001. Main outcome measures: Frequency of anaemia (haemoglobin [Hb] level < 120 g/L) at enrolment and over ensuing 6 months, by tumour type, disease status and cancer treatment; anaemia treatment and “trigger” Hb level for this treatment. Results: Participants had median age 60 years, and 61% were women. Prevalence of anaemia at enrolment was 35% (199/562), with 78% of these 199 having mild anaemia (Hb, 100–119 g/L). Frequency of anaemia (either present at enrolment or developing during the study) was 57% overall (323/566), and varied with tumour type, from 49% (lymphoma/myeloma) to 85% (urogenital cancer). Patients who received radiotherapy either in combination or concomitant with chemotherapy were more likely to have anaemia (73%) than those receiving chemotherapy alone (58%) (P = 0.004). Of all chemotherapy patients not anaemic at enrolment, 23% developed anaemia by the second monthly follow-up. Independent predictors for anaemia in chemotherapy patients were low baseline Hb level (odds ratio [OR], 5.4; 95% CI, 2.7–10.9) and use of platinum chemotherapeutic agents (OR, 4.8; 95% CI, 2.1–11.4) (P < 0.001). Anaemia was treated in 41% of patients with anaemia at enrolment — by transfusion (36%), iron (5%) and erythropoietic agents (2%). Frequency of anaemia treatment varied between tumour types, from 19% (breast cancer) to 60% (leukaemia). The mean “trigger Hb” for initiating transfusion was 95 g/L. Conclusions: Anaemia is prevalent among Australian patients with cancer managed in hospital oncology units. Its management varies between tumour types. Many patients do not receive treatment for their anaemia. | - |
dc.description.statementofresponsibility | Tara Seshadri, H Miles Prince, David R Bell, Paul B Coughlin, Philip P B James, Gary E Richardson, Boris Chern, Peter Briggs, John Norman, Ian N Olver, Chris Karapetis and John Stewart, for the Australia Cancer Anaemia Study (ACAS) Group | - |
dc.language.iso | en | - |
dc.publisher | Australasian Med Publ Co Ltd | - |
dc.source.uri | http://www.mja.com.au/public/issues/182_09_020505/ses10667_fm.html | - |
dc.subject | Australian Cancer Anaemia Study Group | - |
dc.subject | Humans | - |
dc.subject | Neoplasms | - |
dc.subject | Anemia | - |
dc.subject | Incidence | - |
dc.subject | Prevalence | - |
dc.subject | Statistics, Nonparametric | - |
dc.subject | Prospective Studies | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Aged, 80 and over | - |
dc.subject | Middle Aged | - |
dc.subject | Australia | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.title | The Australian Cancer Anaemia Survey: a snapshot of anaemia in adult patients with cancer | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.5694/j.1326-5377.2005.tb06784.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Olver, I. [0000-0001-5478-1576] | - |
Appears in Collections: | Aurora harvest 2 Medicine publications |
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hdl_17458.pdf | Published version | 255.92 kB | Adobe PDF | View/Open |
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