Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/36442
Type: Journal article
Title: Modelling errors in scoring the darkness of staining
Author: Hutchinson, T.
Gudlaugsdottir, S.
Citation: Analytical and Quantitative Cytology and Histology, 2002; 24(2):121-124
Publisher: Sci Printers & Publ Inc
Issue Date: 2002
ISSN: 0884-6812
Statement of
Responsibility: 
T. Paul Hutchinson and Sigurbjorg Gudlaugsdottir
Abstract: Objective: To construct a statistical model for the agreements and disagreements between two observers on darkness of staining. Study Design: Data from an earlier observer-agreement study by van Diest et al were reanalyzed. Results: A model in which the random variation in error is permitted to depend upon the true darkness of staining was found to fit the data much better than does one in which the random variation is constant. Conclusion: For the dataset analyzed, error tends to be greater (that is, correlation between observers tends to be less) when staining is darker.
Keywords: Breast cancer; staining; immunohistochemistry; reproducibility of results; heteroscedasticity of errors
Description: © Science Printers and Publishers
RMID: 0020065381
Description (link): http://www.aqch.com/toc/auto_abstract.php?id=16107
Appears in Collections:Centre for Automotive Safety Research publications

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