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|Title:||Modelling errors in scoring the darkness of staining|
|Citation:||Analytical and Quantitative Cytology and Histology, 2002; 24(2):121-124|
|Publisher:||Sci Printers & Publ Inc|
|T. Paul Hutchinson and Sigurbjorg Gudlaugsdottir|
|Abstract:||Objective: To construct a statistical model for the agreements and disagreements between two observers on darkness of staining. Study Design: Data from an earlier observer-agreement study by van Diest et al were reanalyzed. Results: A model in which the random variation in error is permitted to depend upon the true darkness of staining was found to fit the data much better than does one in which the random variation is constant. Conclusion: For the dataset analyzed, error tends to be greater (that is, correlation between observers tends to be less) when staining is darker.|
|Keywords:||Breast cancer; staining; immunohistochemistry; reproducibility of results; heteroscedasticity of errors|
|Description:||© Science Printers and Publishers|
|Appears in Collections:||Centre for Automotive Safety Research publications|
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