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https://hdl.handle.net/2440/44853
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Type: | Journal article |
Title: | Squamous cell carcinoma presenting as an orbital cyst with radiologic evidence of perineural invasion |
Author: | Limawararut, V. Hoyama, E. Selva-Nayagam, D. Davis, G. |
Citation: | European Journal of Ophthalmology, 2007; 17(6):970-972 |
Publisher: | Wichtig Editore |
Issue Date: | 2007 |
ISSN: | 1120-6721 1724-6016 |
Abstract: | <h4>Purpose</h4>To report clinical and radiologic findings of cystic squamous cell carcinoma (SCC) of the orbit with evidence of perineural involvement.<h4>Methods</h4>Analysis of clinical findings and radiology with a literature review.<h4>Results</h4>A 66-year-old man with SCC of the forehead 8 years prior presented with paraesthesias, diplopia, and proptosis. Magnetic resonance imaging showed a well-defined, cystic mass of the orbit with a single, linear structure running through its center. Lateral orbitotomy revealed a cyst adherent to adjacent periorbita containing viscous, clear, yellow substance and a nerve coursing through the center. Histopathology confirmed poorly differentiated spindle cell carcinoma with positive staining for cytokeratin markers, consistent with SCC.<h4>Conclusions</h4>Orbital cysts associated with altered sensation are suggestive of SCC with perineural spread, requiring prompt investigation and treatment to minimize morbidity and mortality. The involved nerve may be seen as a single, linear structure within the mass on imaging. |
Keywords: | Lacrimal Apparatus Humans Cysts Carcinoma, Squamous Cell Orbital Neoplasms Cranial Nerve Neoplasms Neoplasm Invasiveness Diagnosis, Differential Magnetic Resonance Imaging Aged Male Keratins Biomarkers, Tumor |
DOI: | 10.1177/112067210701700616 |
Published version: | http://dx.doi.org/10.1177/112067210701700616 |
Appears in Collections: | Aurora harvest 6 Medicine publications |
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