Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/56002
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Type: Journal article
Title: The effectiveness of collaborative medicine reviews in delaying time to next hospitalization for patients with heart failure in the practice setting: results of a cohort study
Author: Roughead, E.
Barratt, J.
Ramsay, E.
Pratt, N.
Ryan, P.
Peck, R.
Killer, G.
Gilbert, A.
Citation: Circulation. Heart Failure, 2009; 2(5):424-428
Publisher: Lippincott Williams & Wilkins
Issue Date: 2009
ISSN: 1941-3289
1941-3297
Statement of
Responsibility: 
Elizabeth E. Roughead, John D. Barratt, Emmae Ramsay, Nicole Pratt, Philip Ryan, Robert Peck, Graeme Killer and Andrew L. Gilbert
Abstract: BACKGROUND: Randomized controlled trials have demonstrated that collaborative medication reviews can improve outcomes for patients with heart failure. We aimed to determine whether these results translated into Australian practice, where collaborative reviews are nationally funded. METHODS AND RESULTS: This retrospective cohort study using administrative claims data included veterans 65 years and older receiving bisoprolol, carvedilol, or metoprolol succinate for which prescribing physicians indicated treatment was for heart failure. We compared those exposed to a general practitioner-pharmacist collaborative home medication review with those who did not receive the service. The service includes physician referral, a home visit by an accredited pharmacist to identify medication-related problems, and a pharmacist report with follow-up undertaken by the physician. Kaplan-Meier analyses and Cox proportional hazards models were used to compare time until next hospitalization for heart failure between the exposed and unexposed groups. There were 273 veterans exposed to a home medicines review and 5444 unexposed patients. Average age in both groups was 81.6 years (no significant difference). The median number of comorbidities was 8 in the exposed group and 7 in the unexposed (P<0.0001). Unadjusted results showed a 37% reduction in rate of hospitalization for heart failure at any time (hazard ratio, 0.63; 95% CI, 0.44 to 0.89). Adjusted results showed a 45% reduction (hazard ratio, 0.55; 95% CI, 0.39 to 0.77) among those who had received a home medicines review compared with the unexposed patients. CONCLUSIONS: Medicines review in the practice setting is effective in delaying time to next hospitalization for heart failure in those treated with heart failure medicines.
Keywords: heart failure; morbidity; medication review; hospitalization
Description: Copyright © 2009 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited.
RMID: 0020092876
DOI: 10.1161/CIRCHEARTFAILURE.109.861013
Appears in Collections:Public Health publications

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