Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/8711
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Type: Journal article
Title: Use of sequential DTPA clearance and high resolution computerized tomography in monitoring interstitial lung disease in dermatomyositis
Author: Hill, C.
Romas, E.
Kirkham, B.
Citation: British journal of rheumatology, 1996; 35(2):164-166
Publisher: Oxford University Press (OUP)
Issue Date: 1996
ISSN: 0263-7103
1462-0332
Abstract: Interstitial lung disease complicating polymyositis-dermatomyositis has a grave prognosis. We report the case of a 50-yr-old woman with dermatomyositis and interstitial lung disease monitored by sequential high-resolution computerized tomography (HRCT) of lung and aerosol clearance times of the radionuclide 99Technetium-diethylene triamine pentacetate (DTPA). She was treated with oral cyclophosphamide and prednisolone with good outcome. Pulmonary response to therapy was followed with sequential HRCT and DTPA scanning. DTPA clearance a measure of lung inflammation, and HRCT paralleled clinical course during the treatment of interstitial lung disease. Sequential HRCT and DTPA were useful adjuncts in the initial assessment and monitoring of interstitial lung disease in association with dermatomyositis.
Keywords: Lung
Humans
Dermatomyositis
Lung Diseases, Interstitial
Technetium Tc 99m Pentetate
Cyclophosphamide
Prednisolone
Anti-Inflammatory Agents
Antirheumatic Agents
Tomography, X-Ray Computed
Middle Aged
Female
DOI: 10.1093/rheumatology/35.2.164
Published version: http://dx.doi.org/10.1093/rheumatology/35.2.164
Appears in Collections:Aurora harvest 4
Medicine publications

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