Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/89552
Citations
Scopus Web of Science® Altmetric
?
?
Type: Journal article
Title: Anaemia of pregnancy, perinatal outcomes and children's developmental vulnerability: a whole-of-population study
Author: Smithers, L.
Gialamas, A.
Scheil, W.
Brinkman, S.
Lynch, J.
Citation: Paediatric and Perinatal Epidemiology, 2014; 28(5):381-390
Publisher: Wiley
Issue Date: 2014
ISSN: 0269-5022
1365-3016
Statement of
Responsibility: 
Lisa G. Smithers, Angela Gialamas, Wendy Scheil, Sally Brinkman, John W. Lynch
Abstract: BACKGROUND: There is limited longitudinal data from high-income countries on the sequelae of anaemia during pregnancy. The aim of this study is to examine whether anaemia of pregnancy is associated with adverse perinatal outcomes and with children's developmental vulnerability. METHODS: We conducted a population-based study to link routinely collected government administrative data that involved all live births in the state of South Australia 1999-2005 (n = 124 061) and a subset for whom developmental data were collected during a national census of children attending their first year of school in 2009 (n = 13 654). Perinatal outcomes were recorded by midwives using a validated, standardised form. Development was recorded by schoolteachers using the Australian Early Development Index (AEDI). Children in the lowest 10% of AEDI scores are indicative of developmental vulnerability. RESULTS: There were 8764/124 061 (7.1%) cases of anaemia. After adjustment for a range of potentially confounding factors, anaemia of pregnancy was associated with a higher risk of fetal distress [incident rate ratio (IRR) 1.20 [95% CI 1.13, 1.27]] and preterm birth <37 weeks gestation (IRR 1.23 [1.15, 1.31]), slightly higher birthweight [14 g (2, 26)] and newborns were less likely to require resuscitation (IRR 0.94 [0.91, 0.097]). Anaemia of pregnancy was not associated with children's developmental vulnerability after adjustment for maternal, obstetric and sociodemographic covariables, either in complete case analyses (n = 11 949) or after imputation for missing data (n = 13 654). CONCLUSIONS: Anaemia of pregnancy is associated with perinatal complications but not with children's developmental vulnerability at school entry.
Keywords: anaemia; child development; pregnancy outcome
Rights: © 2014 John Wiley & Sons Ltd
RMID: 0030010722
DOI: 10.1111/ppe.12149
Grant ID: http://purl.org/au-research/grants/nhmrc/1056888
http://purl.org/au-research/grants/nhmrc/570120
Appears in Collections:Public Health publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.