Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9091
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Type: Journal article
Title: A comparison of micromanometric and standard manometric techniques for recording of oesophageal motility
Author: Chen, W.
Omari, T.
Holloway, R.
Checklin, H.
Dent, J.
Citation: Neurogastroenterology and Motility, 1998; 10(3):253-262
Publisher: BLACKWELL SCIENCE LTD
Issue Date: 1998
ISSN: 1350-1925
1365-2982
Abstract: Perfused micromanometric assemblies with an outer diameter of 2 mm or less have been developed for use in premature infants and small laboratory animals. Such assemblies offer advantages with regard to subject comfort and low perfusion rates that make them attractive for use in adults. The aim of this study was to investigate the recording fidelity of micromanometric assemblies in the measurement of oesophageal peristalsis in adults. Two micromanometric assemblies with an outer diameter of 1.8-2.0 mm and a length suitable for use in adults (165 cm), and containing micromanometric lumina of 0.28-0.35 mm i.d. and a standard lumen of 0.6-0.75 mm i.d. were evaluated. Each assembly was tested by measurement of pressure rise rate in response to sudden occlusion, and in vivo during oesophageal peristalsis by simultaneous comparison with an intraluminal strain gauge. At perfusion rates of 0.01-0.15 mL min-1 microlumina achieved pressure rise rates of 21-430 mmHg sec-1 that were comparable to 37-390 mmHg sec-1 for the standard lumina perfused at 0.15-0.6 mL min-1. During oesophageal peristalsis, micromanometric lumina recorded the occurrence and timing of all pressure waves accurately when compared with standard lumina and the microtransducer. However, microlumina under-recorded pressure wave amplitude to varying degrees dependent upon perfusion rate although the performance of microlumina could be improved to that of the standard lumen by shortening their length to 70 cm. Micromanometric assemblies are suitable for recording oesophageal peristalsis in adults although there is some impairment of absolute manometric fidelity. Fidelity can be improved by minimizing total assembly length.
Keywords: Esophagus; Humans; Equipment Design; Manometry; Peristalsis; Pressure; Adult; Middle Aged; Female; Male
RMID: 0030004794
DOI: 10.1046/j.1365-2982.1998.00103.x
Appears in Collections:Medicine publications

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