Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/112112
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Type: | Journal article |
Title: | Miniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissue |
Author: | Li, J. Schartner, E. Musolino, S. Quirk, B. Kirk, R. Ebendorff-Heidepriem, H. McLaughlin, R. |
Citation: | Optics Letters, 2018; 43(8):1682-1685 |
Publisher: | Optical Society of America |
Issue Date: | 2018 |
ISSN: | 0146-9592 1539-4794 |
Statement of Responsibility: | Jiawen Li, Erik Schartner, Stefan Musolino, Bryden C. Quirk, Rodney W. Kirk, Heike Ebendorff-Heidepriem and Robert A. McLaughlin |
Abstract: | The ability to visualize structure whilst simultaneously measuring chemical or physical properties of a biological tissue has the potential to improve our understanding of complex biological processes. We report the first miniaturized single-fiber-based imaging+sensing probe capable of simultaneous optical coherence tomography (OCT) imaging and temperature sensing. An OCT lens is fabricated at the distal end of a double clad fiber, including a thin layer of rare-earth doped tellurite glass to enable temperature measurements. The high refractive index of the tellurite glass enables a common-path interferometer configuration for OCT, allowing easy exchange of probes for biomedical applications. The simultaneous imaging+sensing capability is demonstrated on rat brains. |
Keywords: | Brain Animals Rats Diagnostic Imaging Tomography, Optical Coherence Body Temperature Equipment Design Fiber Optic Technology Optical Fibers |
Rights: | © 2018 Optical Society of America |
DOI: | 10.1364/OL.43.001682 |
Grant ID: | http://purl.org/au-research/grants/arc/CE140100003 http://purl.org/au-research/grants/arc/DP150104660 http://purl.org/au-research/grants/arc/LP110200736 |
Published version: | https://doi.org/10.1364/OL.43.001682 |
Appears in Collections: | Aurora harvest 8 IPAS publications Medicine publications |
Files in This Item:
File | Description | Size | Format | |
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hdl_112112.pdf | Accepted version | 6.13 MB | Adobe PDF | View/Open |
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